JANET E. LAINHART
Janet Lainhart
email: janet.lainhart@hsc.utah.edu		 Associate Professor of Psychiatry and Pediatrics

Faculty, Utah Brain Istitute
Neurobiology of Disease
Brain and Behavior
Developmental Neurobiology

B.S. 1975, Michigan State University; M.D. 1979, Wayne State University School of Medicine. Postgraduate training in Pediatrics and Psychiatry, 1979-1984, 1987-1990, The Johns Hopkins University School of Medicine.

RESEARCH:

Neurobiology of autism

Dr. Lainhart's research focuses on understanding brain growth, development, and maturation in autism from the fetal period into adulthood. She leads a multidisciplinary research group that is conducting a longitudinal neuroimaging study of the brain in autism. Fetal ultrasound, birth and early childhood head circumference, high-resolution structural MRI and diffusion tensor MRI data are integrated with clinical and neuropsychological data. The goals are to define brain phenotypes of autism from the prenatal period into adulthood and understand how changes in brain structure and white matter microstructure are related to clinical symptoms, course, and outcome. The research if funded by the National Institutes of Mental Health and the Autism Speaks Foundation.

Selected Publications

Alexander, A.L., Lee, J.E., Lazar, M., Boudos, R., DuBray, M.B., Oakes, T.R., Miller, J.N., Lu, J., Jeong, E.K., McMahon, W.M., Bigler, E.D., and Lainhart, J.E. (2007) Diffusion tensor imaging of the corpus callosum in Autism. Neuroimage, 34:61-73.

Hobbs, K., Kennedy, A., DuBray, M., Bigler, E.D., Petersen, P.B., McMahon, W., and Lainhart, J.E. (2007) A retrospective fetal ultrasound study of brain size in autism. Biol Psychiatry, 62:1048-1055.

Lee, J.E., Bigler, E.D., Alexander, A.L., Lazar, M., DuBray, M.B., Chung, M.K., Johnson, M., Morgan, J., Miller, J.N., McMahon, W.M., Lu, J., Jeong, E.K., and Lainhart, J.E. (2007) Diffusion tensor imaging of white matter in the superior temporal gyrus and temporal stem in autism. Neurosci Lett, 424:127-132.

Lainhart, J.E. (2006) Advances in autism neuroimaging research for the clinician and geneticist. Am J Med Genet C Semin Med Genet, 142:33-39. Review.

Lainhart, J.E., Lazar, M., Bigler, E., and Alexander, A. (2005) The Brain During Life in Autism: Advances in Neuroimaging Research. In: Recent Developments in Autism Research, Ed. M Casanova, NOVA Science Publishers.

Lainhart, J.E. (2003) Increased rate of head growth during infancy in autism. Journal of the American Medical Association, 290:393-394.

Bigler, E.D., Tate, D.F., Neeley, S., Wolfson, L.F., Miller, M.J., Rice, S.A., Cleavenger, H., Anderson, C., Coon, H., Ozonoff, S., Johnson, M., Dinh, E., Lu, J., McMahon, W., and Lainhart, J.E. (2003) Temporal lobe, autism, and macrocephaly. Am J Neuroradiology, Nov-Dec;24(10):2066-2076.

Lainhart, J.E., Ozonoff, S., Coon, H., Krasny, L., Dinh, E., Nice, J., McMahon, W. (2002) Autism, Regression, and the Broader Autism Phenotype. Am J Medical Genetics, 4:1-7.

Lainhart, J. (1999) The psychiatry of autism: disorders in probands and relatives. International Review of Psychiatry, 11:278-298.

Folstein, S.E., Santangelo, S.L., Gilman, S.E., Piven, J., Landa, R., Lainhart, J., Hein, J., and Wzorek, M. (1999) Predictors of cognitive test patterns in autism families. Journal of Child Psychology and Psychiatry, 40:1117-1128.

Lainhart, J.E., Piven, J., Wzorek, M., Landa, R., Santangelo, S., Coon, H., and Folstein, S. (1997) Macrocephaly in children and adults with autism. Journal of the American Academy of Child and Adolescent Psychiatry 36:282-290.

Reviews
Lainhart, J.E. (1997) Developmental Abnormalities in Autism. Lancet 349:373-374.

Lainhart, J., and Piven, J. (1995) Diagnosis, Treatment and Neurobiology of Autism in Children. Current Opinion in Pediatrics 7:392-400.

Neuroscience Home Page Contact us Search